Programa de Pós-Graduação em Bioquímica – Graduate Program in Biochemistry

Laboratório de Defensas Celulares (LABDEF)

Licenciado en Ciencias Biológicas de la Universidad Federal de Santa Catarina, Magíster y Ph.D. en Fisiología de la Universidad Federal de Rio Grande do Sul. Investigación postdoctoral en Johann Wolfgang Goethe Universitaet, Alemania, Otago University, Nueva Zelanda y Salk Institute, Estados Unidos.

“Su investigación se centra en el estudio de las defensas antioxidantes y la modulación del estado redox celular en situaciones de estrés”

Publicaciones principales

Upregulating Nrf2-dependent antioxidant defenses in Pacific oysters Crassostrea gigas: Investigating the Nrf2/Keap1 pathway in bivalves. Comp Biochem Physiol C Toxicol Pharmacol. 2017; 195:16-26. 

Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells. Free Radic Biol Med. 2017; 108:270-279.

Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells. Toxicol In Vitro. 2017; 42:273-280.

Repeated Methylglyoxal Treatment Depletes Dopamine in the Prefrontal Cortex, and Causes Memory Impairment and Depressive-Like Behavior in Mice. Neurochem Res. 2020; 45(2):354-370.