Programa de Pós-Graduação em Bioquímica – Graduate Program in Biochemistry

Prof. Muller holds an undergraduate degree in Physical Education and a master’s degree, a doctoral degree and a postdoctoral degree in Biochemistry from the Universidade Federal do Rio Grande do Sul (UFRGS). He has worked in international laboratories such as Instituto Ramon y Cajal (Spain), University of Albany (USA) and Lausanne University (Switzerland).

“His research line is aimed at studying the metabolism of the central nervous system with a special focus on neuroendocrine, mainly insulin action in the brain and environmental factors such as aging, models of cerebral dementia, diets, physical exercise and the development of new molecules that can modulate the brain activity and affect disease mechanisms”

Main publications:

Physical Exercise Training Improves Judgment and Problem-Solving and Modulates Serum Biomarkers in Patients with Alzheimer’s Disease. Mol Neurobiol. 2021 doi: 10.1007/s12035-021-02411-z

Effects of zingiber officinale extract supplementation on metabolic and genotoxic parameters in diet-induced obesity in mice. British Journal of Nutrition 2020 doi:10.1017/S0007114520005073

Gold nanoparticles treatment reverses brain damage in alzheimer’s disease model. Molecular Neurobiology. 2020. doi: 10.1007/s12035-019-01780-w.

Intranasal insulin treatment modulates the neurotropic, inflammatory, and oxidant mechanisms in the cortex and hippocampus in a low-grade inflammation model. Peptides doi: 10.1016/j.peptides.2019.170175

Gold nanoparticles prevent cognitive deficits, oxidative stress and inflammation in a rat model of sporadic dementia of Alzheimer’s type. Mater Sci Eng C Mater Biol Appl. 2017 doi: 10.1016/j.msec.2017.03.283