Programa de Pós-Graduação em Bioquímica – Graduate Program in Biochemistry

Laboratory of Experimental Neuropathology (LEN)

Bachelor in Pharmacy (Clinical and Toxicological Analysis) and Master in Science in Biological Sciences (Toxicological Biochemistry) at the Federal University of Santa Maria. PhD in Biological Sciences (Biochemistry) at the Federal University of Rio Grande do Sul and post-doctorate in Neurotoxicology at the Instituto de Investigaciones Biomédicas in Barcelona, Spain. 

“His line of research is focused on the study of mechanisms related to neuropathological processes, with focus on redox biology, neurotoxicology and neuroprotection”.

Main Publications: 

New Probucol Analogues Inhibit Ferroptosis, Improve Mitochondrial Parameters, and Induce Glutathione Peroxidase in HT22 Cells. Molecular Neurobiology, 2020. 57: 3273-3290.

Probucol, a lipid-lowering drug, prevents cognitive and hippocampal synaptic impairments induced by amyloid β peptide in mice. Exp Neurol. 2012; 233(2):767-75. 

Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase. Free Radic Biol Med. 2009; 47(4):449-57. 

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain. Toxicol Appl Pharmacol. 2008; 227(1):147-54.