Programa de Pós-Graduação em Bioquímica – Graduate Program in Biochemistry

Bioenergetics and Oxidative Stress Laboratory (LABOX)

Prof. Latini holds an undergraduate degree in Pharmacy and Biochemistry and a doctoral degree in Chemical Sciences from the National University of Córdoba, Argentina (recognized by the Universidade Federal do Rio Grande do Sul, UFRGS- Brazil). She carried out postdoctoral research at UFRGS, at Harvard Medical School and at the University of Berkeley, United States.

“Her research is focused on the study of tetrahydrobiopterin (BH4) metabolism and mitochondrial energetic function in physiological processes and chronic pathological conditions”

Main Publications:

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature. 2018; 563(7732):564-568.

Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice. Arthritis Rheumatol. 2020; 72(1):57-66.

Tetrahydrobiopterin improves hippocampal nitric oxide-linked long-term memory. Mol Genet Metab. 2018; 125(1-2):104-111.

Exercise-induced immune system response: Anti-inflammatory status on peripheral and central organs. Biochim Biophys Acta Mol Basis Dis. 2020;1866(10):165823.