Manuella Pinto Kaster

Bachelor in Biological Sciences and Ph.D. in Neurosciences at the Federal University of Santa Catarina. Post-doctorate in Neurosciences at the Center for Neurosciences and Cell Biology – Coimbra University, McGovern Institute for Brain Research, MIT, United states, and Mount Sinai School of Medicine, NY, United States.

“Her research is focused on the study of the molecular mechanisms involved in resilience or susceptibility to social stress and dysfunctions in cognitive and emotional behaviors”

Main Publications:

CD300f immunoreceptor is associated with major depressive disorder and decreased microglial metabolic fitness. Proceedings of the National Academy of Sciences of the United States of America, 2020. 1: 1-12.

Stress and signaling pathways regulating autophagy: From behavioral models to psychiatric disorders. Experimental Neurology, 2020; 334: 113485.

NLRP3 Inflammasome-Driven Pathways In Depression: Clinical And Preclinical Findings. Brain, Behavior, and Immunity, 2017; S0889: 30064-30068.

Caffeine acts through neuronal adenosine A receptors to prevent mood and memory dysfunction triggered by chronic stress. Proceedings of the National Academy of Sciences of the United States of America, 2015; 122: 7833/201423088-7838.