Programa de Pós-Graduação em Bioquímica – Graduate Program in Biochemistry

Position: Post-Doctoral Fellow (R-23152)

Institution: Laboratory for Energy Metabolism / Division of Metabolic Disorders, Children’s Hospital of Orange, CA, USA. The hospital is affiliated to UCLA and UCI – This position will be responsible for the design and execution of studies to assess cellular energy metabolism and BH4-related pathways in fibroblasts, iPSC–derived neuronal cells, and genetically-modified animals.  Required: The ideal candidate should possess experience in animal behavior, cell culture, Image J, and related platforms. Experience with the use of a Seahorse Bioanalyzer, HPLC system, and flow cytometer is a plus.

More information in: http://ppgbqa.paginas.ufsc.br/oportunidades/
Website: https://www.choc.org/careers/

The thesis is part of a central line of research at the PPGBQA that seeks to respond to a demand of extreme importance worldwide, the impact of environmental contaminants on organisms. The thesis evaluated the effect of Bisphenol-A (BPA) on male fertility in animal models (Zebra fish and immature rats). BPA is a monomer that constitutes the basic unit of polymers for the production of epoxy resins and polycarbonate plastic that are used in the manufacture of food utensils and packaging. Studies of the metabolic alterations resulting from the exposure of fish and mammals are essential for understanding the impact of BPA contamination. The results of the thesis demonstrated that BPA impairs the homeostasis of intracellular calcium ions (Ca2+) in the testes, testicular energy metabolism and spermatogenesis, through non-genomic and genomic mechanisms, being useful for a broader view of the effects of this contaminant.

Check out the articles derived from the thesis:

Batista-Silva H, Dambrós BF, de Moura KRS, Elie N, Delalande C, Van Der Kraak G, Silva FRMB. Calcium influx and spermatogenesis in the testis and liver enzyme activities in the zebrafish are rapidly modulated by the calcium content of the water. Comp Biochem Physiol A Mol Integr Physiol. 2022. 

Batista-Silva H, Rodrigues K, de Moura KRS, Elie N, Van Der Kraak G, Delalande C, Silva FRMB. In vivo and in vitro short-term bisphenol A exposures disrupt testicular energy metabolism and negatively impact spermatogenesis in zebrafish. Reprod Toxicol. 2022 Jan;107:10-21. 

The work was developed during the Sanduíche Doctorate of the student Tuany Eichwald, oriented by Prof. Dr. Alexandra Latini (LABOX). The non-laboratory period of Dr. Sébastien Talbot at Queen’s University (Ontário – Canada) was financed by the CAPES/PrInt program.

https://www.nature.com/articles/s41586-022-05374-w

Dear students, we disclose the enrollment calendar for 2023/1.

Enrollment period for regular students: 09/02 to 12/02: period for online enrollment in disciplines of the Program itself through the Graduate Academic Control System (CAPG): www.capg.ufsc.br

Enrollment of students from other UFSC programs: as of 02/13: start of enrollment requests for students from other Graduate Programs at UFSC. No term limit. The request must be sent to the e-mail: academico.sipg@contato.ufsc.br

Enrollment in isolated discipline (people from outside UFSC): 02/15, 02/16 and 02/17. Period for requesting enrollment in a separate discipline by the Postgraduate Academic Control System (CAPG).

The semester subjects will be informed at the link: https://ppgbqa.ufsc.br/disciplinas-do-semestre/disciplinas-do-semestre/

More information with SIPG